Selective Reaction Monitoring (SRM)
Biomarker Analysis
Panels of biomarkers from one to one hundred proteins can be quantitatively screened in large numbers of samples. Relative or absolute quantitation can be performed but for large numbers of samples there will need to be at least a few reference proteins with absolute quantitation for normalization purposes. Isotopic tagged reference peptides of the highest quality are used for absolute quantitation.
Protein Quantitation
JadeBio can perform targeted quantitation of proteins from simple or complex mixtures measuring multiple peptides with quick turnaround time utilizing SRM.
| Analysis |
Technology Platform |
Turnaround Time |
| SRM Absolute quantification-assay development |
1D UPLC-SRM with internal standards |
200 proteins/3 months |
| SRM Absolute quantification-assay |
1D UPLC-SRM with internal standards and developed SRM assay |
200 to 600 samples/week |
SRM Panels
We have established human exploratory panels in urine, CSF, and blood plasma. We also have several human disease panels ranging from neurodegenerative diseases to oncology, to diagnose a number of diseases based on the presence of known biomarkers.
Click here for more information about our established panels.
High quality custom SRM panels can be established upon request. For a small panel of proteins, assay development only takes several days for a fast turnaround time. The assay will be fully tested in real biological matrices, and biomarker and pharmacokinetic panels can be combined. Contact us for more information.